Shareholder services

ASX information

Please click here for detailed information on Peplin, Inc. from the Australian Securities Exchange.

Securities trading

As a result of Peplin's October 2007 restructuring in the United States as Peplin, Inc., the electronic transfer system used on the ASX, known as CHESS, cannot be used directly for the transfer of securities of foreign companies. To enable companies such as Peplin to have their securities cleared and settled electronically through CHESS, depositary interests called CDIs are issued.

CDIs confer beneficial ownership in foreign securities, legal title to the securities being held by a depositary, CHESS Depositary Nominees Pty Limited (CDN), a subsidiary of ASX. CDI holders receive all of the economic benefits of actual ownership of the underlying shares or options. Peplin's shares and options now trade on the ASX as CHESS Depositary Interests (CDIs) at an exchange ratio of 20:1.

For more information on CDIs, including the rights and entitlements of CDI holders, please contact Peplin via info@peplin.com or call David Smith, the Chief Financial Officer, at +61-7-3250-1200.

For information on converting your shares to CDIs or vice versa, please see below.

Share registry

Peplin's Australian and United States share register is maintained by Computershare, a world leader in financial services and technology provider for the global securities industry, managing more than 100 million shareholder and employee accounts for over 14,000 corporations in 17 countries on five continents.

Request for Issuance of CDIs (convert USA direct holding to Australian CDI)
All issuance requests for CDIs are to be sent to Computershare Trust Company NA (USA)

Registered USA Share Holders Access and complete a downloadable form available via Computershare's website https://www-us.computershare.com / Shareholder Services / Downloadable Forms / Global Transaction forms / Register Removal Request - US to AU. (https://www-us.computershare.com/Investor/FormsCatalogue.asp)

The share certificate and Global Transaction removal form should be sent by overnight delivery to:

Computershare Investor Services Inc
Attn: Karen Correia - Global Transaction Unit
250 Royall Street
CANTON MA 02021
USA

A manually completed form may be returned via fax to +1-617-360-6841 or emailed to: USAIIGlobalTransactionTeam@computershare.com.

If you have any queries please contact:

Global Transaction Unit NA
Phone: 877-624-5999 (Toll free)
            1-781-575-4086 (Local)
Fax: +1-617-360-6841
Email: USAIIGlobalTransactionTeam@computershare.com

A holding statement for the CDIs will be issued to the relevant security holder.

Market Participants
To lodge via the internet, complete and submit your request via the following site: https://www-us.computershare.com/xSettleUS

• Select from USA to Australia
• Select Peplin Inc from the drop down box and complete all required fields to the form. To lodge your instructions, select the 'Submit' button.

Participants should deliver the securities via DTC to Computershare Trust Company NA ("CTCNA"). CTCNA's DTC Participant Account Number is 2415.

Request for cancellation of CDIs
All cancellation requests for CDIs are to be lodged with Computershare Investor Services Australia.